Terbium-161 NCA
GMP grade available
Terbium-161 in aqueous 0.05M HCl is compliant to the highest quality standards of Good Manufacturing Practice (GMP).
Carrier-free lanthanide (NCA) Terbium-161 is produced by neutron activation of enriched Gadolinium-160 using small and medium research reactors.
As a promising radionuclide for Radioligand Therapy, Terbium-161 exhibits comparable chemical characteristics to known radiolanthanides and providing for a bioequivalence creating a similar biodistribution, however a higher cellular absorbed dose is given to lesions and (micro)metastases.
Radiochemistry Unchanged
Terbium-161 provides for comparable chemical characteristics to known radiolanthanides, allowing the utilization of current radiolabeling techniques, but enabling a higher cellular absorbed dose.
Imaging Optimized
Allowing optimization of the SPECT reconstruction parameters, Terbium-161 may provide for higher spatial resolution SPECT imaging, leading to the detection of smaller lesions that provides input for a further optimized treatment plan.
Radiation Safety Improved
Terbium-161 provides for an immediate decrease in dose rate allowing for a significant improvement in general radiation safety. This optimization of radiation safety may extend current treatment room capacity for Radioligand Therapy or allow for outpatient treatment.
Latest news
- Publishing date:
GMP Terbium-161 product launched by TerThera
TerThera B.V. has officially launched the world’s first GMP-compliant Terbium-161 NCA, setting a new benchmark in the commercial scale production of this promising radionuclide.
- Publishing date:
TerThera reached milestone producing over 200Ci (7.4TBq) Terbium-161
Milestone reached. With the extended geographical reach, we were able to meet the demand for Terbium-161 (Tb-161) on 6 continents by ramping up the production that has led to reaching the threshold 200Ci or 7.4TBq Terbium-161 produced and expedited.
- Publishing date:
Imke Boekestijn joined the TerThera team!
Imke will have an instrumental role as Quality and Validation Engineer to further strengthen the hashtag#Terbium161 platform, safeguarding the highest level of quality and preparing our processes for the next scale-up phase. “Amazing to join TerThera in such a significant role and to experience the impact of a novel and groundbreaking radionuclide, both from an academic and industrial perspective,” said Imke Boekestijn, Quality and Validation Engineer at TerThera.
